Our colleague Argyrios Petras is currently in Florida, attending the 6th World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies ⚡️ The conference covers all aspects of electroporation and pulsed electric field technologies, spanning applications in biology, medicine, food, and environmental technologies. Among the many topics discussed, pulsed field ablation (PFA) for cardiac applications 🫀 is one area of interest.
🎤 Yesterday, @Argyrios presented, on behalf of Luca Pasini, their work entitled: “Impact of Contact Force and Electrode Configuration on Electric Field Distribution in Focal Pulsed Field Ablation: a Computational Study on a Realistic Porcine Geometry.” This work would not have been possible without our collaborators, namely Gerard Amorós Figueras, Zoraida Moreno Weidmann, David Viladés Medel, Aurel Neic, Edward Vigmond, Antoni Ivorra, Jose M Guerra and Luca Gerardo-Giorda.
💡 If you didn't get a chance to attend the talk but are interested in PFA and computational modelling, Argyrios Petras will be at the conference until the end. Feel free to get in touch with him!
🙏 Thank you to the organizers and International Society for Electroporation-Based Technologies and Treatments (ISEBTT) for a great conference!
We are happy to have had the opportunity to present our research and exchange ideas with the international scientific community at #CinC 2026 in Madrid 🇪🇸
📌 Minha Anees presented her work “Parameter Sensitivity Analysis on a Virtual Patient Highlights the Impact of Blood and Tissue Conductivities on High-Power Cardiac RFA Outcomes".
🔗 Link to the paper: https://lnkd.in/dJt2Swut
📌 Luca Gerardo-Giorda presented on behalf of Laura Füssel the work “In-Silico Comparison between In-Vitro and In-Vivo Experimental Setups of Cardiac Radiofrequency Ablation“ .
🔗Link to the paper: https://lnkd.in/d2NY8p23
Thank you to everyone involved in these projects, particularly Luca Pasini, Gerard Amorós Figueras, Zoraida Moreno Weidmann, David Viladés Medel, Jose M Guerra and Argyrios Petras for their valuable contributions and support.
A big thank you to all the organizers for putting together such a great conference 👏! We are already looking forward to more inspiring discussions at #CinC 2027! 🚀
🌟 Curious about life at our Linz Lab for In-Silico Medical Interventions?
This time, we asked our postdoctoral researcher, Argyrios Petras, a few questions to get to know him better. 👀🔬 Let’s find out what he does when things don’t go as planned! 🤔💻
Every patient is different, yet cardiac ablation procedures often rely on the same general approach. Could patient characteristics such as BMI and sex influence how energy is delivered during radiofrequency ablation (RFA)?
Minha Anees and our colleagues investigated this question using 8 patient-specific virtual models and performing 136 simulations 💻 to study how factors as sex and BMI affect electrical conditions during high-power RFA.
The results show that higher BMI is associated with higher baseline impedance, which may influence energy delivery and lesion formation. Furthermore, differences between male and female anatomies were observed although these differences were not statistically significant. Together, these findings suggest that a one-size-fits-all approach may not fully account for patient-specific factors that influence cardiac ablation, highlighting the importance of considering patient variability when optimizing treatment strategies.
Computational modelling can help us better understand these differences and, in the future, support more personalized cardiac ablation. 🫀⚡
Congratulations to Minha Anees, Zoraida Moreno Weidmann, David Viladés Medel, Aurel Neic, Edward Vigmond, Jose M Guerra, Luca Gerardo-Giorda and Argyrios Petras! 👏
🎉 Welcome, Simon Bihoreau, to the Linz Lab for In-Silico Medical Interventions! 🎉
We are very happy to welcome postdoctoral researcher Simon Bihoreau, who joined our team today! 👋
Simon studied engineering at ENSTA Paris before moving to Bordeaux, where he completed his Master’s and PhD at Inria in March 2026. During his PhD, he developed a mathematical model of pulsed-field ablation (PFA), using a multiscale approach to connect cellular-level mechanisms with tissue-scale behavior.
As part of our lab, he will work on the development and numerical implementation of multiscale, time-dependent PFA models, incorporating additional physical mechanisms such as lipid oxidation and its effects across different timescales.
Outside of work, he enjoys running, climbing, history, web development, and video games. 🏃♂️🧗♂️📚🎮
We are very happy to have Simon Bihoreau on board and look forward to the exciting research and collaborations ahead! 🚀
🌟 Curious about life at our Linz Lab for In-Silico Medical Interventions?
This time, we asked our PhD student Luca Pasini a few questions to get to know him better. 👀 We learned more about his work, and some personal insights along the way! Let’s find out whether he prefers coffee or tea! ☕🍵
🎓 Huge congratulations to our colleague Minha Anees, who has just earned her PhD! 🎉👏
Under the supervision of Argyrios Petras and Luca Gerardo-Giorda, Minha successfully defended her dissertation entitled “Patient specific modelling of cardiac RFA procedure” 🫀 💻
Her thesis focuses on the use of patient-specific computational modelling to better understand and improve cardiac radiofrequency ablation (RFA). By analysing the impact of patient anatomy, electrode and patch placement, and differences in tissue properties, her work provides valuable insights into treatment effectiveness and procedural safety, with the aim of supporting more personalised ablation strategies in the future.
Congratulations, Minha Anees, on completing your thesis! Wishing you all the best for the future 🌟
Last Friday, our colleague Davide Baroli presented the outcomes of his work at #VPH2026 🎤
He introduced a thermo-poro-elastic framework that integrates tissue deformation, interstitial fluid transport, and heat transfer using patient geometries, with potential applications of electroporation in skin cancer and low-grade glioma 💻
This work represents an important step towards connecting computational modelling and clinical oncology 🏥🎯
Congratulations to Davide Baroli and his co-authors, Argyrios Petras and Luca Gerardo-Giorda! 🎉
And thank you to the VPH - The Society for In Silico Medicine for a great conference!🫶
🌟 Curious about life at our Linz Lab for In-Silico Medical Interventions?
In our new short video series, our team members share more about themselves, their work, and life in Linz. 👀
First up is Laura Füssel, who is currently pursuing her master’s degree at Johannes Kepler Universität Linz and also works as a student intern at our lab! 🎓💻
Let’s find out what she has to say about her work at the lab and discover Laura’s favourite place on campus! 📍
We are Linz Lab for In-Silico Medical Interventions but what comes to mind when you hear “in-silico”? 🤔
In-silico medicine means using mathematical models and computer simulations to better understand and personalise medical interventions. 💻🩺
In our lab, we develop patient-specific computational models for ablation therapies 🫀, study the efficacy of extracorporeal life support 🫁, investigate the progression of tumors such as gliomas 🧠, and explore many other applications to deliver accurate and reliable in silico tools in medicine.
Our goal? Better predictions, better interventions, and more personalised care 🎯
💡 Do you have a research idea, clinical problem, modelling challenge, or potential collaboration in mind? We'd love to hear from you! Reach out to our postdoctoral researches Argyrios Petras, Beata Ondrusova or Davide Baroli or contact our group leader Luca Gerardo-Giorda 📨
